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Which type of dermal exposure is considered the most serious when dealing with pesticides?

  1. When pesticide is mixed with water

  2. When pesticide is mixed with oil

  3. When pesticide is applied on gloves

  4. When pesticide is aerosolized

The correct answer is: When pesticide is mixed with oil

The most serious type of dermal exposure when dealing with pesticides is associated with the mixing of pesticides with oil. Oil-based formulations can enhance the absorption of the pesticide through the skin significantly more than water-based formulations. This is due to the lipophilic nature of many pesticide active ingredients, which means they have an affinity for fats and oils. When pesticides are mixed with oil, they create a more effective means for the chemicals to penetrate the skin barrier, potentially leading to more severe systemic effects, including toxicity and adverse health outcomes. Aerosolized pesticides, while they pose significant inhalation hazards, primarily involve respiratory exposure rather than dermal exposure. Pesticides applied on gloves may also carry risks; however, the gloves serve as a barrier unless there are defects or contamination. Similarly, mixing pesticides with water generally reduces the likelihood of concentrated dermal exposure compared to oil mixtures. Thus, oil-based pesticide exposure is particularly perilous due to the heightened risk of dermal absorption.